Salma Hayek and Irina Shayk wish Penelope Cruz happy 50th birthday… revealing she’s the ‘best mama’ to two ‘little angels’

Penélope Cruz celebrated her milestone 50th birthday on Sunday, and she received touching Instagram tributes from her celeb pals.

Mexican bombshell Salma Hayek shared a blurry snap of herself with the Oscar winner and her sister Mónica Cruz captioned: 'Happy Birthday Penelope!'

'Thank you God for sending to Earth a special number of years ago an angel,' the 57-year-old Oscar nominee gushed.

'All of us whose crossed paths with her know that she's made our life crazy, exciting, meaningful, inspiring, and taught us the meaning of solidarity and loyalty with so much love. Thank you, to you Penelope, for the little angels that you've mothered into this world. You are an extraordinary woman, and every year even more @penelopecruzoficial!'

Aside from an episode of MTV's Punk'd, Salma and Penélope have only co-starred in one film – the 1880-set Mexican western caper Bandidas back in 2006.

Penélope Cruz celebrated her milestone 50th birthday on Sunday, and she received touching Instagram tributes from her celeb pals (pictured March 5)

Penélope Cruz celebrated her milestone 50th birthday on Sunday, and she received touching Instagram tributes from her celeb pals (pictured March 5)

Joachim Rønning and Espen Sandberg's dismally-reviewed action comedy – also starring Sam Shepard, Steve Zahn, and Dwight Yoakam – only earned $18.3M at the box office back from their $35M budget.

Russian bombshell Irina Shayk also praised Cruz (born Sánchez) for her skills as mother, writing: 'Happiest bday to the most beautiful woman on Earth! Kind, sweet, and funny, and the best mama! @penelopecruzoficial.'

Antonio Banderas has co-starred with the Spanish bombshell three times – in Pedro Almodóvar's 2013 film I'm So Excited! and 2019 film Pain and Glory as well as Gastón Duprat and Mariano Cohn's 2021 film Official Competition.

The 63-year-old Oscar nominee wrote in his tribute to Penélope: 'Very happy birthday dear friend! Happy Birthday @penelopecruzoficial.'

Cruz has been a brand ambassador for the French luxury perfumes and cosmetics house Lancôme as far back as 2010 and the official Instagram account wrote: 'Happy birthday! The epitome of elegance and beauty. Your Lancôme family wishes you a happy birthday @penelopecruzofficial!'

'I'm always worrying about everything, so I don't think I could worry anymore because of turning 50,' the Residente video vixen told the Los Angeles Times last November.

'All my friends are preparing me, like, "You are going to be forced to do a party this time." If you have a party with a lot of your friends that you haven't seen in a long time, you end up super stressed out because you want to give all of them quality time and have conversations. But it's loud and you cannot really hear each other and it becomes so stressful. Maybe I have to learn.'

Penélope is said to maintain her youthful appeal by watching her diet, applying wrinkle creams, taking Bioidentical hormones, working out four times a week, sleeping eight hours a night, and meditating.

Mexican bombshell Salma Hayek (R) shared a blurry snap of herself with the Oscar winner (L) and her sister Mónica Cruz (M) captioned: 'Happy Birthday Penelope! Thank you God for sending to Earth a special number of years ago an angel'

Mexican bombshell Salma Hayek (R) shared a blurry snap of herself with the Oscar winner (L) and her sister Mónica Cruz (M) captioned: 'Happy Birthday Penelope! Thank you God for sending to Earth a special number of years ago an angel'

The 57-year-old Oscar nominee gushed: 'All of us whose crossed paths with her know that she's made our life crazy, exciting, meaningful, inspiring, and taught us the meaning of solidarity and loyalty with so much love. Thank you, to you Penelope, for the little angels that you've mothered into this world. You are an extraordinary woman, and every year even more' (pictured in 2005)

The 57-year-old Oscar nominee gushed: 'All of us whose crossed paths with her know that she's made our life crazy, exciting, meaningful, inspiring, and taught us the meaning of solidarity and loyalty with so much love. Thank you, to you Penelope, for the little angels that you've mothered into this world. You are an extraordinary woman, and every year even more' (pictured in 2005)

Aside from an episode of MTV's Punk'd, Salma and Penélope have only co-starred in one film - the 1880-set Mexican western caper Bandidas back in 2006

Aside from an episode of MTV's Punk'd, Salma and Penélope have only co-starred in one film – the 1880-set Mexican western caper Bandidas back in 2006

Russian bombshell Irina Shayk (R) also praised Cruz (born Sánchez) for her skills as mother, writing: 'Happiest bday to the most beautiful woman on Earth! Kind, sweet, and funny, and the best mama! @penelopecruzoficial'

Russian bombshell Irina Shayk (R) also praised Cruz (born Sánchez) for her skills as mother, writing: 'Happiest bday to the most beautiful woman on Earth! Kind, sweet, and funny, and the best mama! @penelopecruzoficial'

Antonio Banderas has co-starred with the Spanish bombshell three times - in Pedro Almodóvar's 2013 film I'm So Excited! and 2019 film Pain and Glory as well as Gastón Duprat and Mariano Cohn's 2021 film Official Competition (pictured)

Antonio Banderas has co-starred with the Spanish bombshell three times – in Pedro Almodóvar's 2013 film I'm So Excited! and 2019 film Pain and Glory as well as Gastón Duprat and Mariano Cohn's 2021 film Official Competition (pictured)

The 63-year-old Oscar nominee wrote in his tribute to Penélope: 'Very happy birthday dear friend! Happy Birthday @penelopecruzoficial'

The 63-year-old Oscar nominee wrote in his tribute to Penélope: 'Very happy birthday dear friend! Happy Birthday @penelopecruzoficial'

Cruz has been a brand ambassador for the French luxury perfumes and cosmetics house Lanco¿me as far back as 2010 and the official Instagram account wrote: 'Happy birthday! The epitome of elegance and beauty. Your Lanco¿me family wishes you a happy birthday'

Cruz has been a brand ambassador for the French luxury perfumes and cosmetics house Lancôme as far back as 2010 and the official Instagram account wrote: 'Happy birthday! The epitome of elegance and beauty. Your Lancôme family wishes you a happy birthday'

The Residente video vixen told the LA Times last November: All my friends are preparing me, like, "You are going to be forced to do a party this time." If you have a party with a lot of your friends that you haven't seen in a long time, you end up super stressed out because you want to give all of them quality time and have conversations. But it's loud and you cannot really hear each other and it becomes so stressful. Maybe I have to learn'

The Residente video vixen told the LA Times last November: All my friends are preparing me, like, "You are going to be forced to do a party this time." If you have a party with a lot of your friends that you haven't seen in a long time, you end up super stressed out because you want to give all of them quality time and have conversations. But it's loud and you cannot really hear each other and it becomes so stressful. Maybe I have to learn'

Penélope is said to maintain her youthful appeal by watching her diet, applying wrinkle creams, taking Bioidentical hormones, working out four times a week, sleeping eight hours a night, and meditating (pictured February 24)

Penélope is said to maintain her youthful appeal by watching her diet, applying wrinkle creams, taking Bioidentical hormones, working out four times a week, sleeping eight hours a night, and meditating (pictured February 24)

Cruz lives in Madrid with her husband of 13 years - Oscar winner Javier Bardem (R, pictured in 2022) - and their 13-year-old son Leonardo and 10-year-old daughter Luna

Cruz lives in Madrid with her husband of 13 years – Oscar winner Javier Bardem (R, pictured in 2022) – and their 13-year-old son Leonardo and 10-year-old daughter Luna

The Ferrari actress is currently hard at work on the Staten Island, NY set of Maggie Gyllenhaal's Frankenstein film The Bride for Warner Bros. portraying Myrna alongside Christian Bale, Jessie Buckley, Annette Bening, Peter Sarsgaard, and Julianne Houg

The Ferrari actress is currently hard at work on the Staten Island, NY set of Maggie Gyllenhaal's Frankenstein film The Bride for Warner Bros. portraying Myrna alongside Christian Bale, Jessie Buckley, Annette Bening, Peter Sarsgaard, and Julianne Houg

Cruz lives in Madrid with her husband of 13 years – Javier Bardem – and their 13-year-old son Leonardo and 10-year-old daughter Luna.

The Ferrari actress and the 55-year-old Oscar winner – who began dating in 2007 – have co-starred in Jamón, Jamón (1992), Not Love, Just Frenzy (1996), Live Flesh (1997), Don't Tempt Me (2001), Vicky Cristina Barcelona (2008), and The Counsellor (2013).

Before Javier, Penélope previously dated Oscar winner Matt Damon, Oscar winner Matthew McConaughey, and four-time Oscar nominee Tom Cruise.

Cruz is currently hard at work on the Staten Island, NY set of Maggie Gyllenhaal's Frankenstein film The Bride for Warner Bros. portraying Myrna alongside Christian Bale, Jessie Buckley, Annette Bening, Peter Sarsgaard, and Julianne Hough.

The 1930s Chicago-set drama is already scheduled to hit US theaters on October 3, 2025.

The Chanel FW/24 brand ambassador will also reunite with her Elegy director Isabel Coixet for a big-screen adaptation of Elena Ferrante's 2005 novel The Days of Abandonment.

According to Variety, Penélope is set to produce and star as Olga, 'a writer forced to give up her artistic ambitions when her husband suddenly leaves her and their two young daughters.'

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